Symptoms and treatment of Cat lymphoma!

Symptoms and treatment of Cat lymphoma!

Overview

Cat plague is a zoonotic infectious disease. The source of infection is usually various diseased rodents or domestic and wild cats. The main cause of human infection of this disease comes from cats, so every owner has Attention should be paid to the disease.

Causes

Currently known include: FeLV infection, FIV infection, second-hand smoke

Feline Leukemia Virus Infection

Feline leukemia virus (FeLV) provirus integrated into the DNA of lymphocytes can initiate the cancerous process of lymphocytes.

Feline immunodeficiency virus infection

Feline immunodeficiency virus (FIV) infection can increase the risk of lymphoma in cats. Some researchers believe that FIV infection may cause immunosuppression to indirectly cause lymphoma.

Secondhand smoke

The disease is not biased in terms of gender and breed, but cats who have been exposed to cigarette smoke for a long time (second-hand smoke) have a higher risk of lymphoma.

The main symptoms

Multicentric lymphoma

Systemic lymphadenopathy, liver mass, spleen mass, or other organ tissue masses may appear according to the affected organs. When invading superficial lymph nodes (such as axillary lymph nodes, cervical lymph nodes), small broad bean-like masses can be palpable.

Gastrointestinal lymphoma

Common symptoms of the digestive system such as weight loss, vomiting, diarrhea, and anorexia.

Mediastinal lymphoma

Respiratory symptoms such as shortness of breath or difficulty may be accompanied by pleural effusion.

Nasopharyngeal Lymphoma

Symptoms such as increased nose and eye secretions, upper respiratory tract murmur, nose bleeding, etc., facial deformities can occur in severe cases.

Renal lymphoma

Urinary system related symptoms such as polydipsia and polyuria can touch irregularly enlarged kidneys.

Skin lymphoma

Single or multiple nodules in the dermis or subcutaneous tissue.

Central Nervous System Lymphoma

Nervous system symptoms such as coma, abnormal behavior, ataxia, paralysis, paralysis, and blindness.

Diagnostic criteria

Laboratory examination

Blood routine

If lymphoma invades the bone marrow and results in bone marrow suppression, anemia will appear such as decreased blood cell counts and decreased hemoglobin. FeLV/FIV inspection

FeLV positive and FIV positive can support the diagnosis of lymphoma, but positive does not mean that lymphoma is diagnosed, and negative does not exclude lymphoma. Biochemical and urine tests

Invasion of the kidney can be manifested as hyperazotemia and decreased urine specific gravity. Invasion of the liver may show elevated liver enzymes.

Imaging examination

Ultrasound exploration

Cats suffering from intra-abdominal lymphoma often find abnormalities such as enlarged liver, enlarged spleen, changes in liver or spleen echo (mixed echo or multiple hypoechoic areas), thickening of the intestinal wall and other abnormalities.

Other checks

Needle puncture

This method can provide evidence for the diagnosis from the aspects of cell or histopathology. The risk and cost of performing fine needle aspiration biopsy are less than that of biopsy. Commonly sampled organs and tissues include the liver, spleen, mediastinum, kidney, and lymph nodes.

Small bowel biopsy

Samples are taken through abdominal exploration or endoscopy, but the cat’s physical condition needs to be combined to determine whether it is suitable for anesthesia and surgery.

Treatment method

Radiation Therapy

Radiation therapy is very effective for limited single lesions. The combined application of radiotherapy and chemotherapy is quite effective for the treatment of nasal lymphoma and mediastinal lymphoma.

Supportive therapy

Fluids, supplementary nutrition, intubation feeding or other supportive therapies can be selected and implemented according to the location and severity of the lymphoma and the cat’s tolerance to chemotherapy (special circumstances may require adjustment of body fluid balance, antiemetic and antidiarrheal, etc.)

Chemotherapy

Chemotherapy can be divided into combination chemotherapy and single-drug chemotherapy. Currently, combined chemotherapy is mostly used for treatment. The more common combination chemotherapy regimens include chlorambucil + prednisone regimen, COP regimen, CHOP regimen, COPA regimen and so on.

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